Masu bincike na Jami'ar Ibraniyawa sun nuna dalilin da yasa DNA ke rushewa a cikin kwayoyin cutar kansa
Masu bincike na Jami'ar Ibraniyawa sun nuna dalilin da yasa DNA ke rushewa a cikin kwayoyin cutar kansa
Anonim

Lalacewa ga DNA na al'ada alama ce ta ƙwayoyin kansa. Ko da yake an riga an san cewa lalacewa ga sel na yau da kullun yana haifar da damuwa ga kwafi na DNA lokacin da kwayoyin cutar kansa suka mamaye, tushen kwayoyin wannan ya kasance a bayyane.

Yanzu, a karon farko, masu bincike a Jami'ar Ibraniyawa ta Urushalima sun nuna cewa a farkon haɓakar ciwon daji, ƙwayoyin sel suna fama da rashin isassun tubalan gini don tallafawa kwafin DNA na yau da kullun. Yana yiwuwa a dakatar da wannan ta hanyar samar da "tubalan gini" a waje, wanda ke haifar da raguwar lalacewar DNA da ƙananan yuwuwar sel don haɓaka sifofin kansa. Don haka, da fatan, wannan zai iya ba da kariya wata rana daga ci gaban ciwon daji.

A cikin aikin dakin gwaje-gwaje da aka gudanar a Jami'ar Ibrananci, Farfesa Batsheva Kerem na Cibiyar Kimiyyar Rayuwa ta Alexander Silberman da Ph.D. ɗalibi Assaf C. Bester ya nuna cewa rashin aiki mara kyau na yaɗuwar salon salula yana haifar da rashin isasshen matakan tubalan ginin DNA (nucleotides) da ake buƙata don tallafawa kwafin DNA na yau da kullun.

Bayan haka, ta hanyar amfani da al'adun dakin gwaje-gwaje da aka gabatar da kwayoyin cutar kansa, masu binciken sun iya nuna cewa ta hanyar samar da waje na waɗannan tubalan ginin DNA yana yiwuwa a sake farfado da tsarin DNA na al'ada, ta haka ne ya kawar da lalacewar da kwayoyin cutar ciwon daji ke haifarwa da kuma yiwuwar ciwon daji. Wannan shine karo na farko da aka nuna hakan a ko'ina.

Wannan aikin, wanda aka rubuta a cikin wani sabon labarin a cikin mujallar Cell, ya haifar da yiwuwar, in ji masu bincike na Jami'ar Ibrananci, don haɓaka sababbin hanyoyin kariya daga ci gaban da aka rigaya, har ma da yiwuwar haifar da wani nau'i na magani don rage raguwa na DNA.

Shahararren taken