Masana kimiyya suna bin diddigin juyin halitta da yaduwar cutar naman gwari, daya daga cikin manyan kisa a duniya
Masana kimiyya suna bin diddigin juyin halitta da yaduwar cutar naman gwari, daya daga cikin manyan kisa a duniya
Anonim

Wani sabon bincike ya yi karin haske kan asalin cutar fungal da ke daya daga cikin manyan abubuwan da ke haddasa mace-mace daga cututtuka masu alaka da cutar kanjamau. Binciken, wanda aka buga a yau a cikin mujallar PLoS Pathogens, wanda Wellcome Trust da BBSRC suka ba da tallafi, ya nuna yadda mafi yawan nau'i na Cryptococcus neoformans ya samo asali kuma ya bazu daga Afirka da Asiya.

Cryptococcus neoformans wani nau'in nau'in fungi ne mai yawan gaske. Wani nau'in naman gwari na musamman - wanda aka sani da Cryptococcus neoformas iri-iri grubii (Cng) - yana haifar da cutar sankarau a tsakanin marasa lafiya da tsarin garkuwar jiki bayan kamuwa da cutar HIV. An yi imani da sama da miliyan miliyan na cutar sankarau na cryptococcal kowace shekara, wanda ke haifar da mutuwar sama da 600,000. Kamuwa da cuta tare da naman gwari, wanda ke mamaye tsarin juyayi na tsakiya, ana bi da shi tare da tsawon rayuwa na magungunan antifungal, wanda zai iya samun sakamako mara kyau.

Sitali Simwami da Dr Matthew Fisher daga Kwalejin Imperial London, tare da abokan aiki daga St Georges, Jami'ar London, Jami'ar Naresuan, Thailand, da Cibiyar CBS Fungal Biodiversity Centre, Netherlands, sun yi amfani da dabarun tsara kwayoyin halitta don kwatanta bambancin jinsin Cng a 183. samfurori da aka ɗauka daga asibitin da muhalli a Thailand a kan samfurori 77 daga bayanan duniya. Tailandia tana da bullar cutar kanjamau kuma kusan ɗaya cikin biyar masu kamuwa da cutar kanjamau suna kamuwa da cutar cryptococcal.

"Cryptococcal meningitis yana kashe dubban daruruwan mutane a kowace shekara, kusan kamar zazzabin cizon sauro, duk da haka ba a kula da su," in ji Dokta Fisher. "Mun san kadan game da inda ya samo asali da kuma yadda ya samo asali. Idan za mu iya bin diddigin juyin halittarsa ​​da bambancinsa, to za mu iya fara fahimtar inda kwayar cutar ta samo asali, yadda yake cutar da mutane da kuma yadda yake daidaitawa don karuwa - ko ƙasa da haka. Wannan bayanin zai kasance mai mahimmanci don taimaka mana gano abubuwan da za a iya amfani da su a nan gaba."

Masu binciken sun gano cewa Cng a Tailandia yana nuna ƙarancin bambance-bambancen kwayoyin halitta idan aka kwatanta da sauran sassan duniya, musamman Afirka inda yawancin zuriyar ƙwayoyin cuta ke faruwa. Wannan ya nuna cewa alƙarya da naman gwari a Afirka za ta da fadi bakan na virulent damuwa kuma mafi girma rates na karbuwa ga antifungal jiyya, yana ambaton cewa clinicians bukatar biya musamman da hankali ga hadarin miyagun ƙwayoyi-resistant siffofin da naman gwari a nan.

Binciken nasu ya kuma nuna cewa an bullo da kwayar cutar daga Afirka zuwa Asiya a wani lokaci a cikin shekaru 7,000 da suka gabata. Yawancin cututtuka masu yaduwa na ɗan adam ana tsammanin sun bulla a cikin shekaru 11,000 da suka gabata, bayan haɓakar noma da kiwon dabbobi. Musamman ma, yana goyan bayan ra'ayin cewa an shigo da cutar ta hanyar tattabarai masu kamuwa da cuta, waɗanda aka yi amfani da su a cikin gida kusan shekaru 5,000 da suka gabata. Tattabara ta gama-gari, wacce ta samo asali a Afirka, ana ɗaukarta a matsayin mai ɗaukar hoto kuma mai yuwuwar yaduwa na naman gwari, najarta ta zama tushen muhalli gama gari na Cng.

Shahararren taken