An Nuna Magungunan Kaya Don Inganta Sakamakon Cutar MERS Coronavirus A Cikin Birai
An Nuna Magungunan Kaya Don Inganta Sakamakon Cutar MERS Coronavirus A Cikin Birai
Anonim

Shahararrun magungunan kashe kwayoyin cuta guda biyu sun inganta sakamakon asibiti a wani karamin gwaji da aka yi kan birai da suka kamu da cutar numfashi ta gabas ta tsakiya (MERS-CoV). Sakamakon binciken, wanda aka buga a cikin Sept. 8 fitowar Nature Medicine, ya ba likitoci wasu bege don magance cututtuka masu ban mamaki da kuma mummunar mutuwa, wanda a halin yanzu ba shi da magani.

Ribavirin da interferon-alpha 2b, magungunan rigakafi guda biyu da ake amfani da su don magance cutar hanta ta C a cikin mutane, an ba su birai rhesus guda hudu sa'o'i takwas bayan sun kamu da MERS-CoV. Idan aka kwatanta da birai guda hudu da suka kamu da cutar da ba su samu magani ba, biran da ke karbar maganin kashe kwayoyin cuta sun nuna karancin jini da kumburin huhu, da karancin lalacewar nama a cikin huhu, da karancin kwafin kwayar cutar. Birai da aka yi amfani da su tare da maganin rigakafi ba su nuna wahalar numfashi kuma suna da alamun ciwon huhu kaɗan a cikin hoton X-ray na ƙirji.

Tun bayan bullar cutar MERS-CoV a tsakiyar shekarar 2012, an tabbatar da samun mutane 111 da suka kamu da cutar, yayin da wasu 52 suka mutu, akasarin wadanda suka mutu a kasar Saudiyya, a cewar Hukumar Lafiya ta Duniya da kuma rahotannin baya-bayan nan. A halin yanzu, maganin ƙwayar cutar numfashi a cikin mutane yana iyakance ga kulawar tallafi, kamar corticosteroids don rage kumburin huhu da tallafin iska don taimakawa tare da numfashi. Amma la'akari da yawan mace-mace, kulawar tallafi ba ta da tasiri sosai.

Gwajin da masu binciken suka yi kan birai na rhesus macaque wani bibiyar binciken da aka yi a watan Afrilu ne da ke nuna cewa maganin rigakafi ya dakatar da kwayar cutar a cikin al'adun cell.

Masu bincike sun ba da shawarar cewa ya kamata a yi la'akari da haɗin maganin rigakafi a matsayin saƙon farko, amma MERS-CoV ba a warware shi ba.

Dr. Anthony S. Fauci, darektan Cibiyar Kula da Allergy da Cututtuka ta Kasa, kungiyar NIH da ta goyi bayan binciken, ta fada wa jaridar New York Times cewa karamin binciken "ba mai canza wasa bane, amma muhimmin abin lura."

Akwai manyan iyakoki ga binciken. Na farko, birai, da mutane, da kuma hanyoyin da ƙwayoyin cuta ke aikatawa a kowannensu sun bambanta sosai, kuma babu tabbacin shiga tsakani zai yi tasiri a cikin mutane. Wannan gaskiya ne musamman la'akari da ƙananan samfurin.

Bugu da ƙari, an ƙaddamar da shawarar maganin rigakafin cutar sa'o'i takwas bayan kamuwa da cuta, da sauri fiye da yadda za a ba da magani a gaskiya. Hasali ma, Dr. Ziad A. Memish, mataimakin ministan lafiya na kasar Saudiyya ya riga ya gwada hada magunguna biyu ga marasa lafiya, inda ba a samu sakamako mai kyau ba. Ya yi hasashen cewa an fara jinyar a makare, lokacin da majinyata sun riga sun kamu da rashin lafiya.

"Amma idan ni likita ne tare da marasa lafiya na MERS, kuma ba ni da wani abu da zan ba su, ba zan yi shakka ba," Dokta Memish ya gaya wa New York Times. Idan wani ya kamu da cutar, akwai kashi 50 na mace-mace."

Shahararren taken