Kama Ciwon Ciwon Kankara Da Farko: Sauƙaƙan Gwajin Jini Ya Gano Hanyoyin Cuta
Kama Ciwon Ciwon Kankara Da Farko: Sauƙaƙan Gwajin Jini Ya Gano Hanyoyin Cuta
Anonim

Wani sabon gwaji na iya ba da damar gano ciwon daji na pancreatic da wuri, a cewar wani sabon bincike. Masu bincike daga Johns Hopkins sun ƙaddara cewa gwajin jini mai sauƙi na iya bayyana sauye-sauye na epigenetic da ke nuna ci gaban ciwon daji a cikin pancreas - wani sashin glandular da ke cikin tsarin narkewa. Sakamakon binciken na iya canza ƙa'idodin tantance cutar da ke kashe kashi 95 cikin ɗari na Amurkawa 45,220 da take shafa kowace shekara.

Binciken, wanda ya sami tallafin tallafi daga Cibiyar Kula da Lafiya ta Kasa (NIH) Cibiyar Ciwon daji ta kasa, ya nemi kafa sabbin hanyoyin gano cutar kansar pancreatic kafin ya yi latti. A yau, jimlar shekaru biyar na rayuwa ga mutanen da ke fama da ciwon daji na pancreas ya kai kashi 5 cikin dari, saboda ba a gano cutar ba har sai ci gaban tumo ya yadu zuwa wasu sassan jiki ta hanyar metastasis. A cewar Nita Ahuja, mataimakiyar farfesa a fannin ilimin cututtuka, tiyata, da urology a Makarantar Magunguna ta Jami'ar Johns Hopkins kuma jagorar marubucin binciken, sabon binciken na iya wakiltar mataki na farko zuwa ingantaccen dabarun tantancewa.

"Muna da mammograms don tantance cutar kansar nono da kuma na'urar daukar hoto don ciwon daji na hanji amma ba mu da wani abin da zai taimaka mana wajen tantance cutar kansar pancreatic," in ji ta a cikin wata sanarwar manema labarai. "Yayin da yake da nisa sosai, muna tsammanin mun sami alamar ganowa da wuri don ciwon daji na pancreatic wanda zai iya ba mu damar ganowa da kai hari kan cutar a matakin farko fiye da yadda muke yi."

Ta amfani da wata hanya mai mahimmanci da ake kira Methylation on Beads (MOB), Ahuja da abokan aikinta sun sami damar gano sauye-sauye na minti biyu a cikin samfuran jini da aka tattara daga marasa lafiya da ciwon daji na pancreatic. A cikin kashi 81 cikin 100 na samfurori na 42, an samo BNC1 da ADAMTS1 - kwayoyin halitta guda biyu waɗanda ba a samo su tare a cikin samfurori daga marasa lafiya ba tare da ciwon daji na pancreatic ko marasa lafiya tare da tarihin pancreatitis. Tawagar ta gano cewa a cikin kwayoyin cutar daji na pancreatic, ƴan gyare-gyare ga waɗannan kwayoyin halitta suna hana su samar da furotin.

Da fatan, sabon binciken zai hanzarta samar da ingantaccen magani da hanyoyin tantancewa. Wannan ya ce, ana buƙatar ƙarin bincike, kamar yadda sakamakon binciken dole ne a fara maimaita shi a kan babban sikelin. Marubutan sun kuma jaddada cewa sigar gwajin jini na kasuwanci na iya zuwa a kebe shi ga masu hadarin gaske maimakon jama'a.

Source: Novel Methylation Biomarker Panel don Farkon Ganewar Ciwon Kankara Na Pancreatic. Joo Mi Yi, Angela A. Guzzetta, Vasudev Bailey, Stephanie R. Downing, Leander Van Neste, Katherine B Chiappinelli, Brian Keeley, Alejandro Stark, Alexander Herrera, Christopher L Wolfgang, Emmanouil P. Pappou, Christine A. Iacobuzio-Donahue, Michael Goggins, James G. Herman, Tza-Huei Wang, Stephen B. Baylin, da Nita Ahuja. Clin Cancer Res clincanres.3224.2012; An buga OnlineFarkon Oktoba 2, 2013

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